Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa)    
Predicted Functional Partners:
IC63_15750
Pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 0.941
IC63_08540
Proline iminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S33 family.
     
  0.846
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.841
IC63_02130
Hydroxyproline-2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the proline racemase family.
     
 0.831
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.826
IC63_02120
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the proline racemase family.
     
 0.782
IC63_03485
tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.753
IC63_03490
2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.705
IC63_01620
Ornithine cyclodeaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.701
IC63_03475
Diacylglyceryl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.646
Your Current Organism:
Paracoccus sphaerophysae
NCBI taxonomy Id: 690417
Other names: ACCC 05413, HAMBI 3106, P. sphaerophysae, Paracoccus sp. Zy-3, Paracoccus sphaerophysae Deng et al. 2011, strain Zy-3
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