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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IC63_16640Catalyzes the formation hydroxymethylpyrimidine phosphate from hydroxymethylpyrimidine and the formation of of 4-amino-2-methyl-5-diphosphomethylpyrimidine from hydroxymethylpyrimidine phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)    
Predicted Functional Partners:
IC63_11035
Hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
 
 0.999
IC63_03805
Thiamine-phosphate pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.988
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.980
IC63_16650
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.979
IC63_16645
Thiamine biosynthesis protein thio; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.837
IC63_15330
Molybdopterin biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.832
IC63_07805
Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.616
IC63_07220
5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
  
 0.574
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
     
 0.519
IC63_11030
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.494
Your Current Organism:
Paracoccus sphaerophysae
NCBI taxonomy Id: 690417
Other names: ACCC 05413, HAMBI 3106, P. sphaerophysae, Paracoccus sp. Zy-3, Paracoccus sphaerophysae Deng et al. 2011, strain Zy-3
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