STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG48473.1PFAM: ATP dependent DNA ligase, central; ATP dependent DNA ligase, C-terminal; KEGG: sjp:SJA_C1-17220 ATP-dependent DNA ligase. (527 aa)    
Predicted Functional Partners:
AEG48472.1
KEGG: sjp:SJA_C1-17210 putative exonuclease.
 0.989
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.942
AEG49445.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.921
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
    
 0.916
AEG49897.1
KEGG: sjp:SJA_C1-00150 putative ICC-like phosphoesterase.
 
   
 0.817
AEG49928.1
DEAD/H associated domain protein; KEGG: sjp:SJA_C1-00170 Lhr-like helicase; PFAM: DEAD/H associated; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal.
 
    0.804
AEG50350.1
Hydrolase, HAD-superfamily, subfamily IIIA; KEGG: mrd:Mrad2831_1224 HAD superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; Histidinol-phosphate phosphatase; PFAM: Nucleotidyl transferase.
  
 0.799
AEG50656.1
PFAM: 3'-5' exonuclease, PolB-like; KEGG: mch:Mchl_5668 hypothetical protein.
   
 0.698
AEG47726.1
KEGG: sjp:SJA_C1-11430 putative nucleotidyltransferase.
 
 
 0.657
AEG47911.1
KEGG: sjp:SJA_C1-12340 hypothetical protein.
   
 0.627
Your Current Organism:
Sphingobium chlorophenolicum
NCBI taxonomy Id: 690566
Other names: FLAVOBACTERIUM SP. (STRAIN ATCC 39723), Flavobacterium sp. (ATCC 39723), Flavobacterium sp. ATCC 39723, S. chlorophenolicum L-1, Sphingobium chlorophenolicum ATCC 39723, Sphingobium chlorophenolicum L-1, Sphingobium chlorophenolicum str. L-1, Sphingobium chlorophenolicum strain L-1
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