STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG49384.1TIGRFAM: Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG: sjp:SJA_C1-10730 succinate dehydrogenase/fumarate reductase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (609 aa)    
Predicted Functional Partners:
AEG49046.1
TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: sjp:SJA_C1-24370 succinate dehydrogenase iron-sulfur protein; PFAM: Ferredoxin.
 
 0.999
AEG49386.1
KEGG: sjp:SJA_C1-10710 succinate dehydrogenase/fumarate reductase cytochrome b subunit; TIGRFAM: Succinate dehydrogenase, cytochrome b556 subunit; PFAM: Succinate dehydrogenase, cytochrome b subunit.
 
 0.999
AEG49385.1
KEGG: sjp:SJA_C1-10720 succinate dehydrogenase hydrophobic anchor subunit; TIGRFAM: Succinate dehydrogenase, hydrophobic membrane anchor; PFAM: Succinate dehydrogenase, cytochrome b subunit.
 
 0.998
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.995
AEG50791.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.987
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.983
sucC
Succinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.982
AEG49552.1
TIGRFAM: Succinate CoA transferase; KEGG: sjp:SJA_C1-05830 acetyl-CoA hydrolase; PFAM: Acetyl-CoA hydrolase/transferase.
  
 
 0.919
AEG50835.1
KEGG: swi:Swit_2022 indolepyruvate ferredoxin oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
  
 
 0.893
AEG48139.1
TIGRFAM: Fumarylacetoacetase; KEGG: sjp:SJA_C2-01590 fumarylacetoacetase; PFAM: Fumarylacetoacetase, N-terminal; Fumarylacetoacetase, C-terminal-like.
  
 
 0.836
Your Current Organism:
Sphingobium chlorophenolicum
NCBI taxonomy Id: 690566
Other names: FLAVOBACTERIUM SP. (STRAIN ATCC 39723), Flavobacterium sp. (ATCC 39723), Flavobacterium sp. ATCC 39723, S. chlorophenolicum L-1, Sphingobium chlorophenolicum ATCC 39723, Sphingobium chlorophenolicum L-1, Sphingobium chlorophenolicum str. L-1, Sphingobium chlorophenolicum strain L-1
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