Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEG49678.1DNA-cytosine methyltransferase; Manually curated; TIGRFAM: DNA methylase, C-5 cytosine-specific; KEGG: bpl:BURPS1106A_3681 modification methylase HgiDII; PFAM: DNA methylase, C-5 cytosine-specific; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (368 aa)    
Predicted Functional Partners:
AEG49664.1
DNA-cytosine methyltransferase; TIGRFAM: DNA methylase, C-5 cytosine-specific; KEGG: rlg:Rleg_7069 DNA-cytosine methyltransferase; PFAM: DNA methylase, C-5 cytosine-specific; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
  
 
0.929
AEG50074.1
KEGG: DNA-cytosine methyltransferase; TIGRFAM: DNA methylase, C-5 cytosine-specific; PFAM: DNA methylase, C-5 cytosine-specific.
  
  
 
0.928
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.913
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.907
AEG49677.1
PFAM: Protein of unknown function DUF262; KEGG: alv:Alvin_1459 hypothetical protein.
 
  
 0.903
AEG50324.1
KEGG: sjp:SJA_C1-30490 putative nucleosidase; TIGRFAM: 5-methylthioadenosine/S-adenosylhomocysteine nucleosidase, putative; PFAM: Nucleoside phosphorylase.
    
  0.903
AEG49676.1
KEGG: alv:Alvin_1460 hypothetical protein.
 
     0.869
AEG49675.1
Manually curated; TIGRFAM: DNA mismatch endonuclease vsr; KEGG: mno:Mnod_4985 DNA mismatch endonuclease Vsr; PFAM: DNA mismatch endonuclease vsr.
 
   
 0.826
AEG50072.1
Manually curated; TIGRFAM: DNA mismatch endonuclease vsr; KEGG: xoo:XOO0606 XorII very-short-patch-repair endonuclease; PFAM: DNA mismatch endonuclease vsr.
 
   
 0.549
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.470
Your Current Organism:
Sphingobium chlorophenolicum
NCBI taxonomy Id: 690566
Other names: FLAVOBACTERIUM SP. (STRAIN ATCC 39723), Flavobacterium sp. (ATCC 39723), Flavobacterium sp. ATCC 39723, S. chlorophenolicum L-1, Sphingobium chlorophenolicum ATCC 39723, Sphingobium chlorophenolicum L-1, Sphingobium chlorophenolicum str. L-1, Sphingobium chlorophenolicum strain L-1
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