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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (433 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
AEG51074.1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
 0.939
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.892
purQ
Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
  
 
 0.881
AEG49577.1
KEGG: sjp:SJA_C1-02400 glutamate synthase (NADPH) large chain; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
    
 0.880
atpA
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
 
    
 0.861
AEG48695.1
TIGRFAM: Glutamine synthetase type I; KEGG: sjp:SJA_C1-19370 glutamine synthetase; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp.
    
 0.858
AEG49579.1
TIGRFAM: Glutamate synthase, NADH/NADPH, small subunit 2; KEGG: sjp:SJA_C1-02420 glutamate synthase (NADPH) small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
    
 0.838
AEG51109.1
Response regulator receiver protein; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region; Signal transduction response regulator, receiver region; KEGG: bid:Bind_1961 response regulator receiver protein; SMART: Signal transduction response regulator, receiver region.
    
 0.833
glsA
PFAM: Glutaminase, core; TIGRFAM: glutaminase A; HAMAP: Glutaminase, core; KEGG: sjp:SJA_C1-21570 glutaminase; Belongs to the glutaminase family.
    
 0.824
Your Current Organism:
Sphingobium chlorophenolicum
NCBI taxonomy Id: 690566
Other names: FLAVOBACTERIUM SP. (STRAIN ATCC 39723), Flavobacterium sp. (ATCC 39723), Flavobacterium sp. ATCC 39723, S. chlorophenolicum L-1, Sphingobium chlorophenolicum ATCC 39723, Sphingobium chlorophenolicum L-1, Sphingobium chlorophenolicum str. L-1, Sphingobium chlorophenolicum strain L-1
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