STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (244 aa)    
Predicted Functional Partners:
Desaf_1960
KEGG: CinA domain-containing protein; TIGRFAM: CinA, C-terminal; PFAM: CinA, C-terminal; Belongs to the CinA family.
 
 
 0.957
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.946
Desaf_1979
PFAM: Quinolinate phosphoribosyl transferase; KEGG: dma:DMR_20580 hypothetical protein.
  
 
 0.937
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.937
Desaf_2918
TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; KEGG: dvm:DvMF_0524 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
    
 0.934
Desaf_3793
NAD-dependent deacetylase; KEGG: drt:Dret_2495 silent information regulator protein Sir2; HAMAP: NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2.
   
 0.933
Desaf_3473
NAD(+) diphosphatase; KEGG: gme:Gmet_0714 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; Zinc ribbon, NADH pyrophosphatase; NADH pyrophosphatase-like, N-terminal.
     
 0.908
Desaf_2046
KEGG: MazG family protein; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core.
    
 0.906
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.904
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
  
  
 0.888
Your Current Organism:
Desulfocurvibacter africanus
NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay
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