STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Desaf_1024TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: cvi:CV_4129 udpglucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (435 aa)    
Predicted Functional Partners:
glmU
Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
 
 0.933
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
    
  0.908
Desaf_0527
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: sat:SYN_02671 pleiotrophic regulatory protein; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.876
lpxA
Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
    
 0.834
Desaf_1016
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: emi:Emin_0863 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.815
Desaf_1143
KEGG: dba:Dbac_3291 undecaprenyl-phosphate glucose phosphotransferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase, WcaJ; Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase.
  
 0.756
Desaf_1394
Hypothetical protein; KEGG: rpc:RPC_2049 PP-loop.
  
  
 0.669
Desaf_2415
UDP-glucuronate 5'-epimerase; KEGG: dde:Dde_0033 NAD-dependent epimerase/dehydratase family protein; PFAM: NAD-dependent epimerase/dehydratase.
 
  
 0.664
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
  
 0.649
Desaf_1501
Oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; KEGG: oxidoreductase domain-containing protein.
 
  
 0.628
Your Current Organism:
Desulfocurvibacter africanus
NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.