STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Desaf_2139PFAM: Nickel-dependent hydrogenase, large subunit; KEGG: hut:Huta_2605 nickel-dependent hydrogenase large subunit. (460 aa)    
Predicted Functional Partners:
Desaf_2138
PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: hut:Huta_2604 NADH ubiquinone oxidoreductase 20 kDa subunit.
 
 
 0.976
Desaf_1385
PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: dat:HRM2_11730 MvhG.
 
 
 0.945
Desaf_2136
KEGG: dly:Dehly_0927 response regulator receiver protein.
 
   
 0.888
Desaf_2137
PFAM: Oxidoreductase FAD-binding region; Oxidoreductase FAD/NAD(P)-binding; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; KEGG: dly:Dehly_0927 response regulator receiver protein.
 
   
 0.887
Desaf_2877
Dihydroorotate dehydrogenase, electron transfer subunit protein; KEGG: dba:Dbac_0854 oxidoreductase FAD/NAD(P)-binding domain protein; iron-sulfur cluster binding domain-containing protein; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase FAD-binding region.
 
   
 0.752
Desaf_0165
Acylphosphatase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.750
Desaf_0132
KEGG: dba:Dbac_0139 hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein; Belongs to the HypD family.
 
   
 0.725
Desaf_0131
KEGG: dba:Dbac_0140 hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein.
 
   
 0.717
Desaf_0336
PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_0232 methyl-viologen-reducing hydrogenase delta subunit.
  
  
 0.705
Desaf_2878
KEGG: dsa:Desal_0597 hydrogenase, putative.
 
     0.692
Your Current Organism:
Desulfocurvibacter africanus
NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay
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