STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa)    
Predicted Functional Partners:
Desaf_2181
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
Desaf_1265
PFAM: Aldehyde dehydrogenase; KEGG: ava:Ava_3615 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.945
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.935
Desaf_1251
Butyrate--CoA ligase; KEGG: dma:DMR_19670 putative acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase/ligase.
   
 
 0.935
Desaf_1391
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
   
 
 0.935
Desaf_0794
CoA-binding domain protein; PFAM: CoA-binding; ATP-grasp fold, succinyl-CoA synthetase-type; KEGG: CoA-binding domain-containing protein.
    
 0.920
Desaf_2335
Acylphosphatase; KEGG: rxy:Rxyl_0794 acylphosphatase; HAMAP: Acylphosphatase; PFAM: Acylphosphatase-like.
     
 0.914
Desaf_2179
Lactate utilization protein B/C; PFAM: Protein of unknown function DUF162; KEGG: dba:Dbac_1728 protein of unknown function DUF162.
  
  
 0.872
Desaf_2407
DRTGG domain protein; PFAM: DRTGG; KEGG: dvm:DvMF_0242 DRTGG domain protein.
 
  
 0.837
Desaf_0793
PFAM: DRTGG; KEGG: DRTGG domain-containing protein.
 
  
 0.826
Your Current Organism:
Desulfocurvibacter africanus
NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay
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