STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (322 aa)    
Predicted Functional Partners:
bioA
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family.
  
 0.997
Desaf_0990
KEGG: dak:DaAHT2_1534 8-amino-7-oxononanoate synthase; PFAM: Aminotransferase, class I/II.
  
 0.975
Desaf_0992
PFAM: Methyltransferase type 11; KEGG: gdj:Gdia_0144 dethiobiotin synthase.
 
  
 0.967
Desaf_3135
KEGG: dsa:Desal_2038 biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase.
  
 
 0.937
Desaf_0236
KEGG: dvl:Dvul_1663 thiamine biosynthesis protein ThiC; TIGRFAM: Thiamine biosynthesis protein ThiC; PFAM: Thiamine biosynthesis protein ThiC.
 
  
 0.804
Desaf_2295
Regulatory protein TetR; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: dma:DMR_26350 TetR family transcriptional regulator.
 
   
 0.584
Desaf_3296
PFAM: BioY protein; KEGG: BioY protein.
  
  
 0.567
Desaf_2917
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
  
  
 0.561
argD
PFAM: Aminotransferase class-III; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; KEGG: dma:DMR_45620 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.516
Desaf_2344
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.495
Your Current Organism:
Desulfocurvibacter africanus
NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay
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