STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Desaf_2326Methyl-accepting chemotaxis sensory transducer with Cache sensor; KEGG: gsu:GSU0400 methyl-accepting chemotaxis protein; PFAM: Cache, type 2; HAMP linker domain; Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling. (583 aa)    
Predicted Functional Partners:
Desaf_0834
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 0.993
Desaf_1443
KEGG: gme:Gmet_2710 CheA signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; CheW-like protein; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; CheW-like protein.
 
 
 0.978
Desaf_3153
KEGG: dsa:Desal_2724 CheA signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup, homodimeric; CheW-like protein; SMART: CheW-like protein; Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPase-like.
 
 0.976
Desaf_3046
KEGG: dde:Dde_2106 CheA signal transduction histidine kinase; PFAM: CheW-like protein; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup, homodimeric; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: CheW-like protein; Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPase-like.
 
 0.973
Desaf_0130
KEGG: dma:DMR_26640 chemotaxis protein CheV; PFAM: CheW-like protein; Signal transduction response regulator, receiver region; SMART: CheW-like protein; Signal transduction response regulator, receiver region.
 
 0.955
Desaf_3612
KEGG: dde:Dde_2040 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein.
 
 0.954
Desaf_2727
KEGG: dvm:DvMF_0284 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein.
 
 0.951
Desaf_1440
PFAM: MCP methyltransferase, CheR-type; Tetratricopeptide TPR-1; KEGG: pol:Bpro_2459 MCP methyltransferase, CheR-type; SMART: MCP methyltransferase, CheR-type; Tetratricopeptide repeat.
 
 0.948
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.946
Desaf_3158
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.943
Your Current Organism:
Desulfocurvibacter africanus
NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay
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