node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Desaf_1576 | Desaf_3405 | Desaf_1576 | Desaf_3405 | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | 0.864 |
Desaf_1576 | Desaf_3409 | Desaf_1576 | Desaf_3409 | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | KEGG: dma:DMR_33280 cell division protein FtsW; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.959 |
Desaf_1576 | Desaf_3414 | Desaf_1576 | Desaf_3414 | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | KEGG: dsa:Desal_0697 peptidoglycan glycosyltransferase; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA. | 0.940 |
Desaf_1576 | mraY | Desaf_1576 | Desaf_3411 | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.473 |
Desaf_1576 | mrdB | Desaf_1576 | Desaf_1577 | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.999 |
Desaf_1576 | murC | Desaf_1576 | Desaf_3407 | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.596 |
Desaf_1576 | murD | Desaf_1576 | Desaf_3410 | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.586 |
Desaf_1576 | murE | Desaf_1576 | Desaf_3413 | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.792 |
Desaf_1576 | murF | Desaf_1576 | Desaf_3412 | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.746 |
Desaf_1576 | murG | Desaf_1576 | Desaf_3408 | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.534 |
Desaf_3405 | Desaf_1576 | Desaf_3405 | Desaf_1576 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; manually curated; KEGG: dsa:Desal_3462 penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. | 0.864 |
Desaf_3405 | Desaf_3409 | Desaf_3405 | Desaf_3409 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | KEGG: dma:DMR_33280 cell division protein FtsW; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.987 |
Desaf_3405 | Desaf_3414 | Desaf_3405 | Desaf_3414 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | KEGG: dsa:Desal_0697 peptidoglycan glycosyltransferase; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA. | 0.962 |
Desaf_3405 | mraY | Desaf_3405 | Desaf_3411 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.933 |
Desaf_3405 | mrdB | Desaf_3405 | Desaf_1577 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.879 |
Desaf_3405 | murC | Desaf_3405 | Desaf_3407 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.979 |
Desaf_3405 | murD | Desaf_3405 | Desaf_3410 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.976 |
Desaf_3405 | murE | Desaf_3405 | Desaf_3413 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.897 |
Desaf_3405 | murF | Desaf_3405 | Desaf_3412 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.930 |
Desaf_3405 | murG | Desaf_3405 | Desaf_3408 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.978 |