Desaf_3543 protein (Desulfocurvibacter africanus)

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second shell of interactors

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filled nodes:
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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

Desaf_3543

KEGG: dvm:DvMF_1305 tail fiber protein, putative. (738 aa)

Predicted Functional Partners:

Desaf_3547

0.946

Desaf_3546

0.944

Desaf_3562

0.909

Desaf_3567

0.906

Desaf_3563

0.905

Desaf_3557

0.887

Desaf_3535

0.886

Desaf_3566

0.886

Desaf_3556

0.882

Desaf_3534

0.875

Your Current Organism:

Desulfocurvibacter africanus

NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
Desaf_3534	Desaf_3535	KEGG: aco:Amico_1103 phage tail protein I; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	0.989
Desaf_3534	Desaf_3543	KEGG: aco:Amico_1103 phage tail protein I; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	KEGG: dvm:DvMF_1305 tail fiber protein, putative.	0.875
Desaf_3534	Desaf_3547	KEGG: aco:Amico_1103 phage tail protein I; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	0.956
Desaf_3534	Desaf_3557	KEGG: aco:Amico_1103 phage tail protein I; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	0.956
Desaf_3534	Desaf_3562	KEGG: aco:Amico_1103 phage tail protein I; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	PFAM: Phage late control D; KEGG: aco:Amico_1109 late control D family protein.	0.947
Desaf_3534	Desaf_3563	KEGG: aco:Amico_1103 phage tail protein I; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	PFAM: Phage tail protein X; KEGG: dbr:Deba_1579 putative phage tail protein gpX.	0.968
Desaf_3534	Desaf_3566	KEGG: aco:Amico_1103 phage tail protein I; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	PFAM: Phage major tail tube protein; KEGG: spe:Spro_4913 major tail tube protein.	0.970
Desaf_3534	Desaf_3567	KEGG: aco:Amico_1103 phage tail protein I; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	KEGG: dbr:Deba_1584 hypothetical protein.	0.972
Desaf_3535	Desaf_3534	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	KEGG: aco:Amico_1103 phage tail protein I; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	0.989
Desaf_3535	Desaf_3543	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	KEGG: dvm:DvMF_1305 tail fiber protein, putative.	0.886
Desaf_3535	Desaf_3546	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	KEGG: drm:Dred_1221 hypothetical protein; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	0.956
Desaf_3535	Desaf_3556	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	KEGG: drm:Dred_1221 hypothetical protein; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	0.956
Desaf_3535	Desaf_3562	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	PFAM: Phage late control D; KEGG: aco:Amico_1109 late control D family protein.	0.948
Desaf_3535	Desaf_3563	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	PFAM: Phage tail protein X; KEGG: dbr:Deba_1579 putative phage tail protein gpX.	0.972
Desaf_3535	Desaf_3566	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	PFAM: Phage major tail tube protein; KEGG: spe:Spro_4913 major tail tube protein.	0.971
Desaf_3535	Desaf_3567	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	KEGG: dbr:Deba_1584 hypothetical protein.	0.969
Desaf_3543	Desaf_3534	KEGG: dvm:DvMF_1305 tail fiber protein, putative.	KEGG: aco:Amico_1103 phage tail protein I; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	0.875
Desaf_3543	Desaf_3535	KEGG: dvm:DvMF_1305 tail fiber protein, putative.	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	0.886
Desaf_3543	Desaf_3546	KEGG: dvm:DvMF_1305 tail fiber protein, putative.	KEGG: drm:Dred_1221 hypothetical protein; TIGRFAM: Phage tail protein I; PFAM: Phage tail protein I.	0.944
Desaf_3543	Desaf_3547	KEGG: dvm:DvMF_1305 tail fiber protein, putative.	PFAM: Baseplate assembly protein J-like, predicted; KEGG: aco:Amico_1104 baseplate J family protein.	0.946

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

27

PPI enrichment p-value:

8.8e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0010133

Proline catabolic process to glutamate

4 of 5

2.35

2.57

1.13e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016620

Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

5 of 8

2.24

3.39

1.37e-07

GO:0016491

Oxidoreductase activity

6 of 250

0.82

0.52

0.0180

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4299

Mixed, incl. LUD domain, and Cysteine-rich domain

5 of 15

1.97

2.64

2.10e-06

CL:1273

Proline catabolic process

3 of 5

2.22

1.91

0.00021

CL:4301

Mixed, incl. Acyl-CoA reductase (LuxC), and NUDIX domain

3 of 6

2.14

1.83

0.00028

CL:4294

Mixed, incl. Phenylalanine metabolism, and Protein of unknown function DUF2911

6 of 77

1.34

1.47

4.30e-05

CL:1061

Mixed, incl. Carbon metabolism, and Cellular amino acid metabolic process

5 of 180

0.89

0.57

0.0159

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00360

Phenylalanine metabolism

4 of 29

1.58

0.00019

map01120

Microbial metabolism in diverse environments

7 of 161

1.08

1.12

3.95e-05

map01100

Metabolic pathways

9 of 937

0.43

0.3

0.0261

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00171

Aldehyde dehydrogenase family

4 of 4

2.44

2.93

2.56e-06

PF05893

Acyl-CoA reductase (LuxC)

2 of 2

2.44

1.01

0.0143

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR016161

Aldehyde/histidinol dehydrogenase

6 of 6

2.44

4.72

3.97e-10

IPR016163

Aldehyde dehydrogenase, C-terminal

5 of 5

2.44

3.87

2.76e-08

IPR016162

Aldehyde dehydrogenase, N-terminal

5 of 5

2.44

3.87

2.76e-08

IPR015590

Aldehyde dehydrogenase domain

5 of 5

2.44

3.87

2.76e-08

IPR029510

Aldehyde dehydrogenase, glutamic acid active site

3 of 3

2.44

2.04

0.00015

(more ...)

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