GAT34744.1 protein (Terrimicrobium sacchariphilum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

GAT34744.1

Right handed beta helix region. (819 aa)

Predicted Functional Partners:

GAT33053.1

0.833

GAT33051.1

0.828

GAT33597.1

0.631

GAT32485.1

0.631

GAT32486.1

0.631

GAT35224.1

0.631

GAT34590.1

0.572

GAT35566.1

0.572

GAT32973.1

0.534

GAT35189.1

0.513

Your Current Organism:

Terrimicrobium sacchariphilum

NCBI taxonomy Id: 690879
Other names: CGMCC 1.5168, JCM 17479, Spartobacteria bacterium NM5, T. sacchariphilum, Terrimicrobium sacchariphilum Qiu et al. 2014 emend. Hahnke et al. 2016, strain NM-5

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAT32485.1	GAT32486.1	TSACC_2884	TSACC_2885	PEP-CTERM protein-sorting domain-containing protein.	PEP-CTERM protein-sorting domain-containing protein.	0.672
GAT32485.1	GAT33051.1	TSACC_2884	TSACC_21456	PEP-CTERM protein-sorting domain-containing protein.	Right handed beta helix region.	0.513
GAT32485.1	GAT33597.1	TSACC_2884	TSACC_22014	PEP-CTERM protein-sorting domain-containing protein.	PEP-CTERM protein-sorting domain-containing protein.	0.420
GAT32485.1	GAT34590.1	TSACC_2884	TSACC_23021	PEP-CTERM protein-sorting domain-containing protein.	Alpha-glucosidase.	0.443
GAT32485.1	GAT34744.1	TSACC_2884	TSACC_23177	PEP-CTERM protein-sorting domain-containing protein.	Right handed beta helix region.	0.631
GAT32485.1	GAT35224.1	TSACC_2884	TSACC_3288	PEP-CTERM protein-sorting domain-containing protein.	PEP-CTERM protein-sorting domain-containing protein.	0.593
GAT32486.1	GAT32485.1	TSACC_2885	TSACC_2884	PEP-CTERM protein-sorting domain-containing protein.	PEP-CTERM protein-sorting domain-containing protein.	0.672
GAT32486.1	GAT33051.1	TSACC_2885	TSACC_21456	PEP-CTERM protein-sorting domain-containing protein.	Right handed beta helix region.	0.481
GAT32486.1	GAT33597.1	TSACC_2885	TSACC_22014	PEP-CTERM protein-sorting domain-containing protein.	PEP-CTERM protein-sorting domain-containing protein.	0.420
GAT32486.1	GAT34590.1	TSACC_2885	TSACC_23021	PEP-CTERM protein-sorting domain-containing protein.	Alpha-glucosidase.	0.443
GAT32486.1	GAT34744.1	TSACC_2885	TSACC_23177	PEP-CTERM protein-sorting domain-containing protein.	Right handed beta helix region.	0.631
GAT32486.1	GAT35224.1	TSACC_2885	TSACC_3288	PEP-CTERM protein-sorting domain-containing protein.	PEP-CTERM protein-sorting domain-containing protein.	0.594
GAT32973.1	GAT33051.1	TSACC_21377	TSACC_21456	Hypothetical protein.	Right handed beta helix region.	0.423
GAT32973.1	GAT34590.1	TSACC_21377	TSACC_23021	Hypothetical protein.	Alpha-glucosidase.	0.458
GAT32973.1	GAT34744.1	TSACC_21377	TSACC_23177	Hypothetical protein.	Right handed beta helix region.	0.534
GAT33051.1	GAT32485.1	TSACC_21456	TSACC_2884	Right handed beta helix region.	PEP-CTERM protein-sorting domain-containing protein.	0.513
GAT33051.1	GAT32486.1	TSACC_21456	TSACC_2885	Right handed beta helix region.	PEP-CTERM protein-sorting domain-containing protein.	0.481
GAT33051.1	GAT32973.1	TSACC_21456	TSACC_21377	Right handed beta helix region.	Hypothetical protein.	0.423
GAT33051.1	GAT33053.1	TSACC_21456	TSACC_21458	Right handed beta helix region.	Right handed beta helix region.	0.512
GAT33051.1	GAT34744.1	TSACC_21456	TSACC_23177	Right handed beta helix region.	Right handed beta helix region.	0.828

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

38

average node degree:

6.91

avg. local clustering coefficient:

0.966

expected number of edges:

21

PPI enrichment p-value:

0.000804

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

7 of 107

1.23

1.39

1.72e-05

GO:0010467

Gene expression

9 of 201

1.07

1.21

2.67e-06

GO:0061077

Chaperone-mediated protein folding

2 of 2

2.42

1.18

0.0068

GO:0032978

Protein insertion into membrane from inner side

2 of 2

2.42

1.18

0.0068

GO:0022417

Protein maturation by protein folding

2 of 2

2.42

1.18

0.0068

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

7 of 51

1.55

2.33

1.66e-07

GO:0019843

rRNA binding

4 of 39

1.43

1.1

0.0025

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

7 of 61

1.48

2.2

1.18e-07

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:112

Ribosome

7 of 59

1.49

2.14

3.38e-07

CL:115

Ribosome

6 of 52

1.48

2.02

1.08e-06

CL:97

Ribosome, and Ribonucleoside triphosphate biosynthetic process

8 of 102

1.31

1.77

3.38e-07

CL:118

Ribosome

5 of 47

1.44

1.65

2.86e-05

CL:120

rRNA-binding, and Structural constituent of ribosome

4 of 36

1.46

1.37

0.00039

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

dao03010

Ribosome

7 of 53

1.54

2.43

3.53e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 50

1.56

2.44

6.41e-08

GOCC:0044391

Ribosomal subunit

4 of 26

1.6

1.59

0.00019

GOCC:0022626

Cytosolic ribosome

3 of 21

1.57

1.18

0.0025

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 10

1.72

0.82

0.0240

GOCC:0015934

Large ribosomal subunit

2 of 13

1.6

0.73

0.0341

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

7 of 62

1.47

2.14

2.06e-07

KW-0699

rRNA-binding

4 of 37

1.45

1.28

0.00073

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00935

Outer membrane protein (OmpH-like)

2 of 2

2.42

1.14

0.0081

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