Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
GAT32500.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 0.993
GAT32769.1
2-oxoglutarate dehydrogenase E1 component.
 0.987
GAT35403.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit.
  
 0.951
GAT32770.1
2-oxoglutarate dehydrogenase E2 component.
 
 0.934
GAT32029.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.918
GAT35404.1
Succinate dehydrogenase / fumarate reductase flavoprotein subunit.
  
 0.912
TSACC_277
Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.895
GAT33222.1
F-type H+-transporting ATPase subunit delta.
   
 
 0.879
GAT33745.1
Aconitate hydratase.
  
 0.871
Your Current Organism:
Terrimicrobium sacchariphilum
NCBI taxonomy Id: 690879
Other names: CGMCC 1.5168, JCM 17479, Spartobacteria bacterium NM5, T. sacchariphilum, Terrimicrobium sacchariphilum Qiu et al. 2014 emend. Hahnke et al. 2016, strain NM-5
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