GAT32443.1 protein (Terrimicrobium sacchariphilum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GAT32443.1

Regulatory protein, luxR family. (254 aa)

Predicted Functional Partners:

GAT32764.1

0.806

GAT33113.1

0.806

GAT35053.1

0.802

GAT34258.1

0.783

GAT32372.1

0.783

GAT33615.1

0.779

GAT34935.1

0.779

GAT31960.1

0.758

TSACC_397

0.758

TSACC_138

0.585

Your Current Organism:

Terrimicrobium sacchariphilum

NCBI taxonomy Id: 690879
Other names: CGMCC 1.5168, JCM 17479, Spartobacteria bacterium NM5, T. sacchariphilum, Terrimicrobium sacchariphilum Qiu et al. 2014 emend. Hahnke et al. 2016, strain NM-5

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAT31960.1	GAT32372.1	TSACC_2356	TSACC_2770	Signal transduction histidine kinase.	PAS domain S-box-containing protein.	0.999
GAT31960.1	GAT32443.1	TSACC_2356	TSACC_2841	Signal transduction histidine kinase.	Regulatory protein, luxR family.	0.758
GAT31960.1	GAT32764.1	TSACC_2356	TSACC_21165	Signal transduction histidine kinase.	PAS domain S-box-containing protein.	0.999
GAT31960.1	GAT33113.1	TSACC_2356	TSACC_21522	Signal transduction histidine kinase.	PAS domain S-box-containing protein.	0.999
GAT31960.1	GAT33615.1	TSACC_2356	TSACC_22032	Signal transduction histidine kinase.	PAS domain S-box-containing protein.	0.999
GAT31960.1	GAT34258.1	TSACC_2356	TSACC_22683	Signal transduction histidine kinase.	PAS domain S-box-containing protein.	0.999
GAT31960.1	GAT34935.1	TSACC_2356	TSACC_23369	Signal transduction histidine kinase.	Ammonium transporter.	0.999
GAT31960.1	GAT35053.1	TSACC_2356	TSACC_3113	Signal transduction histidine kinase.	Signal transduction histidine kinase.	0.999
GAT31960.1	TSACC_138	TSACC_2356	TSACC_138	Signal transduction histidine kinase.	Regulatory protein, luxR family.	0.999
GAT31960.1	TSACC_397	TSACC_2356	TSACC_397	Signal transduction histidine kinase.	HPt (histidine-containing phosphotransfer) domain-containing protein.	0.999
GAT32372.1	GAT31960.1	TSACC_2770	TSACC_2356	PAS domain S-box-containing protein.	Signal transduction histidine kinase.	0.999
GAT32372.1	GAT32443.1	TSACC_2770	TSACC_2841	PAS domain S-box-containing protein.	Regulatory protein, luxR family.	0.783
GAT32372.1	GAT32764.1	TSACC_2770	TSACC_21165	PAS domain S-box-containing protein.	PAS domain S-box-containing protein.	0.999
GAT32372.1	GAT33113.1	TSACC_2770	TSACC_21522	PAS domain S-box-containing protein.	PAS domain S-box-containing protein.	0.999
GAT32372.1	GAT33615.1	TSACC_2770	TSACC_22032	PAS domain S-box-containing protein.	PAS domain S-box-containing protein.	0.999
GAT32372.1	GAT34258.1	TSACC_2770	TSACC_22683	PAS domain S-box-containing protein.	PAS domain S-box-containing protein.	0.999
GAT32372.1	GAT34935.1	TSACC_2770	TSACC_23369	PAS domain S-box-containing protein.	Ammonium transporter.	0.999
GAT32372.1	GAT35053.1	TSACC_2770	TSACC_3113	PAS domain S-box-containing protein.	Signal transduction histidine kinase.	0.999
GAT32372.1	TSACC_138	TSACC_2770	TSACC_138	PAS domain S-box-containing protein.	Regulatory protein, luxR family.	0.998
GAT32372.1	TSACC_397	TSACC_2770	TSACC_397	PAS domain S-box-containing protein.	HPt (histidine-containing phosphotransfer) domain-containing protein.	0.999

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.943

expected number of edges:

12

PPI enrichment p-value:

0.000143

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 108

1.51

3.17

5.08e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

11 of 44

1.9

5.69

3.25e-18

GO:0003735

Structural constituent of ribosome

11 of 57

1.79

4.94

2.08e-17

GO:0000049

tRNA binding

3 of 28

1.54

0.96

0.0086

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 61

1.76

4.81

1.34e-17

GO:0044391

Ribosomal subunit

5 of 18

1.95

3.17

6.42e-08

GO:0015934

Large ribosomal subunit

4 of 9

2.15

3.06

5.22e-07

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:129

rRNA-binding

9 of 11

2.42

7.84

9.15e-18

CL:126

Ribosome

10 of 23

2.14

6.86

4.97e-18

CL:123

Ribosome

11 of 40

1.94

5.98

1.46e-18

CL:131

Mixed, incl. Large ribosomal subunit, and K Homology domain, type 2

6 of 6

2.51

5.6

6.70e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

apak03010

Ribosome

11 of 56

1.8

5.07

5.14e-18

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044391

Ribosomal subunit

8 of 25

2.01

4.93

4.88e-13

GOCC:0005840

Ribosome

9 of 46

1.8

4.2

3.79e-13

GOCC:0015934

Large ribosomal subunit

5 of 10

2.2

3.84

9.67e-09

GOCC:0022626

Cytosolic ribosome

4 of 20

1.81

2.16

1.51e-05

GOCC:0015935

Small ribosomal subunit

3 of 15

1.81

1.62

0.00038

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

11 of 41

1.93

6.01

5.11e-19

KW-0689

Ribosomal protein

11 of 58

1.78

4.96

7.72e-18

KW-0820

tRNA-binding

3 of 18

1.73

1.37

0.0013

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