Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSACC_313Nickel-dependent lactate racemase. (418 aa)    
Predicted Functional Partners:
GAT35282.1
Hypothetical protein.
 
  
 0.861
GAT32174.1
Hypothetical protein.
 
  
 0.842
TSACC_314
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family.
 
     0.842
GAT32500.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.810
larC
Hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.763
GAT31887.1
FAD/FMN-containing dehydrogenase.
    
  0.760
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
 0.672
GAT35408.1
Malate dehydrogenase.
 
  
  0.670
GAT35299.1
(S)-2-hydroxy-acid oxidase/4-hydroxymandelate oxidase.
     
  0.599
GAT33860.1
4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis.
     
  0.567
Your Current Organism:
Terrimicrobium sacchariphilum
NCBI taxonomy Id: 690879
Other names: CGMCC 1.5168, JCM 17479, Spartobacteria bacterium NM5, T. sacchariphilum, Terrimicrobium sacchariphilum Qiu et al. 2014 emend. Hahnke et al. 2016, strain NM-5
Server load: medium (64%) [HD]