Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSACC_396NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (227 aa)    
Predicted Functional Partners:
GAT34419.1
Acyl transferase domain-containing protein.
 
 0.913
GAT33654.1
Glutamate synthase (NADPH/NADH) large chain.
     
 0.797
TSACC_395
Chloride channel protein, CIC family.
   
   0.785
GAT32500.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
   
 0.774
TSACC_323
Non-ribosomal peptide synthetase component F.
  
 0.756
TSACC_283
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
 0.696
TSACC_334
Nucleoside-diphosphate kinase; Belongs to the NDK family.
 
  
   0.672
TSACC_314
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family.
  
     0.653
fabZ
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
  
 
 0.642
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
   
   0.610
Your Current Organism:
Terrimicrobium sacchariphilum
NCBI taxonomy Id: 690879
Other names: CGMCC 1.5168, JCM 17479, Spartobacteria bacterium NM5, T. sacchariphilum, Terrimicrobium sacchariphilum Qiu et al. 2014 emend. Hahnke et al. 2016, strain NM-5
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