STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSACC_396NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (227 aa)    
Predicted Functional Partners:
GAT34419.1
Acyl transferase domain-containing protein.
 
 0.922
GAT32500.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
   
 0.892
GAT33654.1
Glutamate synthase (NADPH/NADH) large chain.
     
 0.857
fabZ
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
  
 0.828
TSACC_323
Non-ribosomal peptide synthetase component F.
  
 0.804
TSACC_395
Chloride channel protein, CIC family.
  
 
 0.794
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 0.736
TSACC_283
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.729
TSACC_334
Nucleoside-diphosphate kinase; Belongs to the NDK family.
 
  
   0.675
TSACC_314
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family.
  
     0.653
Your Current Organism:
Terrimicrobium sacchariphilum
NCBI taxonomy Id: 690879
Other names: CGMCC 1.5168, JCM 17479, Spartobacteria bacterium NM5, T. sacchariphilum, Terrimicrobium sacchariphilum Qiu et al. 2014 emend. Hahnke et al. 2016, strain NM-5
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