STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
ANQ20972.1Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)    
Predicted Functional Partners:
ANQ20973.1
Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
EntE
(2,3-dihydroxybenzoyl)adenylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.998
ANQ20974.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.993
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 0.967
ANQ21988.1
Anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.947
menF
Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
  
  
 
0.926
ANQ20970.1
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.916
ubiC
Chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.
     
 0.908
tyrA
Bifunctional chorismate mutase/prephenate dehydrogenase; Catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.891
PheA
Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.887
Your Current Organism:
Vibrio natriegens
NCBI taxonomy Id: 691
Other names: ATCC 14048, Beneckea natriegens, CAIM 12, CCUG 16371, CCUG 4980 A, CIP 103193, DSM 759, IFO 15636, LMG 10935, LMG:10935, NBRC 15636, NCCB 73019, NCMB 857, NCMB:857, NCTC 11319, Pseudomonas natriegens, V. natriegens
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