STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htpXZinc metalloprotease HtpX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M48B family. (289 aa)    
Predicted Functional Partners:
ANQ21253.1
Cyclopropane-fatty-acyl-phospholipid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.539
ANQ23107.1
Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.531
ANQ21250.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.485
ANQ21251.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.485
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
  
  
 0.481
ANQ21252.1
FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.471
ANQ21254.1
Zinc ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.471
ANQ21255.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.471
msrB-2
Methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.465
ANQ23108.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.463
Your Current Organism:
Vibrio natriegens
NCBI taxonomy Id: 691
Other names: ATCC 14048, Beneckea natriegens, CAIM 12, CCUG 16371, CCUG 4980 A, CIP 103193, DSM 759, IFO 15636, LMG 10935, LMG:10935, NBRC 15636, NCCB 73019, NCMB 857, NCMB:857, NCTC 11319, Pseudomonas natriegens, V. natriegens
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