Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANQ22305.1Hypothetical protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (483 aa)    
Predicted Functional Partners:
ANQ22306.1
Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.894
ANQ22307.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.855
ANQ22308.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.846
lptD
LPS assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
  
  
 0.680
ANQ22303.1
AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.673
ANQ22304.1
sirA-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
       0.673
surA
Peptidylprolyl isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
 
  
 0.639
ANQ22843.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.634
TolC
Outer membrane channel protein TolC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.632
ANQ23020.1
Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.511
Your Current Organism:
Vibrio natriegens
NCBI taxonomy Id: 691
Other names: ATCC 14048, Beneckea natriegens, CAIM 12, CCUG 16371, CCUG 4980 A, CIP 103193, DSM 759, IFO 15636, LMG 10935, LMG:10935, NBRC 15636, NCCB 73019, NCMB 857, NCMB:857, NCTC 11319, Pseudomonas natriegens, V. natriegens
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