H696_01126 protein (Fonticula alba) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

H696_01126

Uncharacterized protein. (1387 aa)

Predicted Functional Partners:

H696_02891

0.910

H696_01463

0.828

H696_04530

0.792

H696_04116

0.764

H696_01995

0.764

H696_04102

0.754

H696_04105

0.754

H696_01118

0.735

H696_02044

0.722

H696_00744

0.705

Your Current Organism:

Fonticula alba

NCBI taxonomy Id: 691883
Other names: F. alba

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H696_00744	H696_01126	A0A058ZGV9	A0A058ZCP4	Uncharacterized protein.	Uncharacterized protein.	0.705
H696_00744	H696_01995	A0A058ZGV9	A0A058ZAT2	Uncharacterized protein.	Calmodulin; Belongs to the calmodulin family.	0.533
H696_00744	H696_02891	A0A058ZGV9	A0A058Z8H7	Uncharacterized protein.	Myb-like domain-containing protein.	0.999
H696_00744	H696_04116	A0A058ZGV9	A0A058Z5Y9	Uncharacterized protein.	Calmodulin.	0.533
H696_01118	H696_01126	A0A058ZB93	A0A058ZCP4	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	Uncharacterized protein.	0.735
H696_01118	H696_01463	A0A058ZB93	A0A058ZCE7	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	WD_REPEATS_REGION domain-containing protein.	0.970
H696_01118	H696_02044	A0A058ZB93	A0A058ZCD5	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	CP-type G domain-containing protein.	0.999
H696_01118	H696_04102	A0A058ZB93	A0A058Z5Z7	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	Uncharacterized protein.	0.732
H696_01118	H696_04105	A0A058ZB93	A0A058Z6Y7	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	Ipi1_N domain-containing protein.	0.732
H696_01118	H696_04530	A0A058ZB93	A0A058Z4A5	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.999
H696_01126	H696_00744	A0A058ZCP4	A0A058ZGV9	Uncharacterized protein.	Uncharacterized protein.	0.705
H696_01126	H696_01118	A0A058ZCP4	A0A058ZB93	Uncharacterized protein.	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	0.735
H696_01126	H696_01463	A0A058ZCP4	A0A058ZCE7	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.828
H696_01126	H696_01995	A0A058ZCP4	A0A058ZAT2	Uncharacterized protein.	Calmodulin; Belongs to the calmodulin family.	0.764
H696_01126	H696_02044	A0A058ZCP4	A0A058ZCD5	Uncharacterized protein.	CP-type G domain-containing protein.	0.722
H696_01126	H696_02891	A0A058ZCP4	A0A058Z8H7	Uncharacterized protein.	Myb-like domain-containing protein.	0.910
H696_01126	H696_04102	A0A058ZCP4	A0A058Z5Z7	Uncharacterized protein.	Uncharacterized protein.	0.754
H696_01126	H696_04105	A0A058ZCP4	A0A058Z6Y7	Uncharacterized protein.	Ipi1_N domain-containing protein.	0.754
H696_01126	H696_04116	A0A058ZCP4	A0A058Z5Y9	Uncharacterized protein.	Calmodulin.	0.764
H696_01126	H696_04530	A0A058ZCP4	A0A058Z4A5	Uncharacterized protein.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.792

page 1 of 3

Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070006

Metalloaminopeptidase activity

4 of 9

2.41

2.88

3.04e-06

GO:0030145

Manganese ion binding

3 of 9

2.29

2.03

0.00013

GO:0046914

Transition metal ion binding

5 of 110

1.42

1.46

0.00013

GO:0046872

Metal ion binding

8 of 627

0.87

0.8

0.00013

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005965

Protein farnesyltransferase complex

2 of 3

2.59

1.03

0.0132

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:8231

Mixed, incl. Pyrimidine nucleotide-sugar transmembrane transport, and Macromolecule depalmitoylation

6 of 35

2.0

3.43

2.02e-08

CL:8236

Pyrimidine nucleotide-sugar transmembrane transport, and Aminopeptidase activity

5 of 21

2.14

3.34

1.05e-07

CL:6054

Terpenoid backbone biosynthesis, and Short chain dehydrogenase

4 of 22

2.02

2.37

1.31e-05

CL:8258

Pyrimidine nucleotide-sugar transmembrane transport, and Aminopeptidase P, N-terminal

3 of 10

2.24

1.96

0.00017

CL:8260

Nucleotide-sugar transporter, and Aminopeptidase P, N-terminal

2 of 5

2.37

1.18

0.0066

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00900

Terpenoid backbone biosynthesis

4 of 20

2.06

2.55

5.82e-06

map00260

Glycine, serine and threonine metabolism

4 of 20

2.06

2.55

5.82e-06

map01100

Metabolic pathways

8 of 959

0.68

0.55

0.0011

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005965

Protein farnesyltransferase complex

2 of 3

2.59

0.99

0.0156

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0464

Manganese

3 of 12

2.16

1.81

0.00031

KW-0031

Aminopeptidase

2 of 11

2.02

0.93

0.0172

KW-0479

Metal-binding

5 of 353

0.91

0.58

0.0172

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00557

Metallopeptidase family M24

4 of 10

2.37

2.81

3.81e-06

PF00432

Prenyltransferase and squalene oxidase repeat

2 of 3

2.59

1.08

0.0108

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029149

Creatinase/Aminopeptidase P/Spt16, N-terminal

4 of 5

2.67

3.13

1.48e-06

IPR036005

Creatinase/aminopeptidase-like

4 of 10

2.37

2.72

5.86e-06

IPR000994

Peptidase M24

4 of 10

2.37

2.72

5.86e-06

IPR007865

Aminopeptidase P, N-terminal

3 of 3

2.76

2.36

4.70e-05

IPR045089

Prenyltransferase subunit beta

2 of 3

2.59

1.03

0.0133

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01011

Aminopeptidase P, N-terminal domain

3 of 3

2.76

2.55

2.05e-05

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (16%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About