STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H696_002712-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (438 aa)    
Predicted Functional Partners:
H696_05628
2-oxoisovalerate dehydrogenase E1 component, beta subunit.
 0.999
H696_00937
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
H696_00985
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.990
H696_04511
Dihydrolipoyl dehydrogenase.
 
 
 0.967
H696_03129
2-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase).
  
 0.964
H696_02005
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.964
H696_05974
Uncharacterized protein.
 
 
 0.963
H696_00849
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.
  
 
 0.926
H696_05159
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.925
H696_01530
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.921
Your Current Organism:
Fonticula alba
NCBI taxonomy Id: 691883
Other names: F. alba
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.