STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H696_002712-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (438 aa)    
Predicted Functional Partners:
H696_05628
2-oxoisovalerate dehydrogenase E1 component, beta subunit.
 0.999
H696_00937
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.995
H696_00985
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.989
H696_04511
Dihydrolipoyl dehydrogenase.
  
 
 0.973
H696_00108
Isovaleryl-CoA dehydrogenase, mitochondrial.
  
 
 0.910
H696_04700
Acyl-CoA dehydrogenase.
  
 
 0.898
H696_02005
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.894
H696_05580
Branched-chain amino acid aminotransferase.
    
 0.887
H696_06384
Uncharacterized protein.
     
 0.887
H696_05577
Uncharacterized protein.
    
 0.887
Your Current Organism:
Fonticula alba
NCBI taxonomy Id: 691883
Other names: F. alba
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.