Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3N416_GASACRetinoblastoma-like 1 (p107). (1066 aa)    
Predicted Functional Partners:
G3NFG8_GASAC
Transcription factor.
   
 0.994
G3PKY1_GASAC
E2F transcription factor 4.
   
 0.992
G3PXY3_GASAC
E2F transcription factor 5.
   
 0.992
CCNE2
Cyclin E2; Belongs to the cyclin family.
   
 0.985
G3PG64_GASAC
Cyclin E1; Belongs to the cyclin family.
   
 0.985
G3Q0P6_GASAC
Cyclin E2; Belongs to the cyclin family.
   
 0.985
G3N5X5_GASAC
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.979
G3NLM0_GASAC
E2F transcription factor 1.
   
 0.962
E2F3
E2F transcription factor 3.
   
 0.951
G3P4V1_GASAC
Si:ch211-160f23.5.
   
 0.951
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: low (20%) [HD]