STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3N434_GASACChromodomain helicase DNA binding protein 6. (2577 aa)    
Predicted Functional Partners:
G3NRM5_GASAC
Catenin (cadherin-associated protein), beta 1.
   
 0.853
G3PQA7_GASAC
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.819
G3Q0Y4_GASAC
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.809
G3Q530_GASAC
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 
 0.806
G3PEW6_GASAC
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.804
G3NJ04_GASAC
Retinoblastoma binding protein 5.
    
 
 0.762
G3NIY0_GASAC
AT rich interactive domain 4A (RBP1-like).
   
 0.755
G3NK22_GASAC
Translocase of outer mitochondrial membrane 20.
   
 0.755
G3N724_GASAC
Ash2 like, histone lysine methyltransferase complex subunit.
    
 
 0.752
G3NMN1_GASAC
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
   
 0.725
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.