Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3N468_GASACProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (182 aa)    
Predicted Functional Partners:
G3NZ94_GASAC
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.962
G3N651_GASAC
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.917
G3NXM0_GASAC
Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.907
G3NMF6_GASAC
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.906
G3NLK4_GASAC
Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.905
FZD3
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.905
G3NBP6_GASAC
Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.896
G3NAG3_GASAC
Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.888
G3PMA2_GASAC
Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.884
G3P0Z0_GASAC
Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.883
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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