Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GATA2GATA binding protein 2. (455 aa)    
Predicted Functional Partners:
G3NDE6_GASAC
Zinc finger protein, FOG family member 1.
    
 0.939
G3PL07_GASAC
T-cell acute lymphocytic leukemia 1.
   
 0.936
G3PS93_GASAC
Spi-1 proto-oncogene b.
    
 0.934
G3PRA9_GASAC
Runt-related transcription factor.
    
 0.874
G3P624_GASAC
LIM domain only 2 (rhombotin-like 1).
    
 0.863
G3NI63_GASAC
T-box transcription factor 21.
    
 0.852
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.846
G3NWF7_GASAC
Runt-related transcription factor.
    
 0.805
G3PFC2_GASAC
Runt-related transcription factor.
    
 0.805
G3NM42_GASAC
E1A binding protein p300 a.
    
 0.787
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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