STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GIYD1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (265 aa)    
Predicted Functional Partners:
G3Q4I3_GASAC
Uncharacterized protein.
   
 0.999
G3Q4N8_GASAC
MUS81 structure-specific endonuclease subunit.
   
 0.994
G3N6B1_GASAC
Asparaginyl-tRNA synthetase.
   
 0.982
G3P9V9_GASAC
BLM RecQ like helicase.
    
 0.980
G3PR64_GASAC
Uncharacterized protein.
    
 0.978
G3NSL9_GASAC
Excision repair cross-complementation group 1.
   
 0.975
G3NKI9_GASAC
Excision repair cross-complementation group 4.
   
 0.971
G3NY50_GASAC
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.962
G3P4E5_GASAC
Uncharacterized protein.
   
 0.962
G3NXN3_GASAC
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae).
    
 0.958
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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