Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3N7D3_GASACSorting nexin 7. (425 aa)    
Predicted Functional Partners:
G3PMC7_GASAC
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.888
G3NSS1_GASAC
PX domain-containing protein.
   
 
 0.883
SNX4
Sorting nexin 4.
   
 
 0.883
G3N871_GASAC
Biogenesis of lysosomal organelles complex-1, subunit 2.
    
 
 0.859
G3P782_GASAC
Zgc:92912.
    
 0.845
G3QAA3_GASAC
Vesicle-associated membrane protein 2.
    
 0.845
G3NJD2_GASAC
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.784
G3NLM4_GASAC
Sorting nexin 5.
   
 0.784
G3NLK9_GASAC
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.770
G3N6A2_GASAC
Si:dkey-28n18.9.
   
 0.751
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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