Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3N7Y2_GASACTPR_REGION domain-containing protein. (126 aa)    
Predicted Functional Partners:
G3NXN3_GASAC
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae).
    
 
 0.960
G3NY50_GASAC
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 
 0.946
G3P9V9_GASAC
BLM RecQ like helicase.
  
 
 0.942
G3P4E5_GASAC
Uncharacterized protein.
  
 0.920
G3NBZ1_GASAC
Exonuclease 1.
  
 0.913
G3NQJ7_GASAC
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.903
G3NW76_GASAC
Serine/threonine-protein kinase PLK.
   
 0.884
G3PKU2_GASAC
Serine/threonine-protein kinase PLK.
   
 0.884
PLK1
Serine/threonine-protein kinase PLK.
   
 0.884
G3N9U6_GASAC
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.873
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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