Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
USP24Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family. (1604 aa)    
Predicted Functional Partners:
G3NNN2_GASAC
Damage-specific DNA binding protein 2.
    
 0.992
G3P2G0_GASAC
Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.
      
 0.904
G3QA52_GASAC
Ubiquitin B.
    
  0.900
G3P326_GASAC
Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.
      
 0.897
G3NX84_GASAC
Thyroid hormone receptor interactor 12.
   
 
 0.866
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.844
G3NBE1_GASAC
Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family.
   
 
 0.813
G3NZ68_GASAC
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.761
G3PVY7_GASAC
Epidermal growth factor.
      
 0.738
G3PCG6_GASAC
Ribosomal protein S27a.
    
  0.737
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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