STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3N8K5_GASAC3-hydroxy-3-methylglutaryl coenzyme A reductase. (887 aa)    
Predicted Functional Partners:
G3Q3W0_GASAC
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.993
G3P3B0_GASAC
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
  
 0.954
G3PTV2_GASAC
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
 
 0.936
G3NNG8_GASAC
UbiA prenyltransferase domain containing 1.
   
 
 0.934
G3NLR2_GASAC
Squalene epoxidase a.
  
  
 0.931
G3NJG1_GASAC
Cytochrome P450, family 51; Belongs to the cytochrome P450 family.
  
  
 0.911
G3N889_GASAC
Non-specific serine/threonine protein kinase.
    
 0.864
G3PTT2_GASAC
Non-specific serine/threonine protein kinase.
    
 0.864
G3PT43_GASAC
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
  
 
0.843
G3N9G6_GASAC
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
   
 
 0.825
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.