STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3N8M1_GASACAnaphylatoxin-like domain-containing protein. (472 aa)    
Predicted Functional Partners:
G3N969_GASAC
Uncharacterized protein.
 
    0.920
G3N8L1_GASAC
A2M_N_2 domain-containing protein.
 
    0.913
G3PPM4_GASAC
NTR domain-containing protein.
 
 
 0.883
G3N599_GASAC
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.868
G3PPI0_GASAC
Uncharacterized protein.
   
 0.868
G3QBM8_GASAC
Complement factor b, like; Belongs to the peptidase S1 family.
   
 0.860
G3Q1B8_GASAC
Complement component 6.
   
 0.855
C8A
Complement C8 alpha chain.
   
 0.830
G3ND28_GASAC
Complement component 8, gamma polypeptide; Belongs to the calycin superfamily. Lipocalin family.
   
 0.819
G3NR28_GASAC
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.815
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.