Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
G3N8W8_GASACUncharacterized protein. (375 aa)    
Predicted Functional Partners:
G3PNJ4_GASAC
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.973
G3Q4T1_GASAC
WASP like actin nucleation promoting factor b.
   
 0.972
G3N821_GASAC
Profilin; Belongs to the profilin family.
   
 0.970
G3NWQ0_GASAC
Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
   
 0.970
G3P398_GASAC
Profilin; Belongs to the profilin family.
   
 0.970
G3PUE0_GASAC
Profilin; Belongs to the profilin family.
   
 0.970
G3PZK8_GASAC
IQ motif containing GTPase activating protein 1.
    
 0.968
G3NJF0_GASAC
Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.
   
 0.967
G3PY12_GASAC
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 0.967
G3NBU9_GASAC
Vinculin b.
   
 0.962
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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