STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3N8X4_GASACStaufen double-stranded RNA binding protein 1. (715 aa)    
Predicted Functional Partners:
G3Q9N5_GASAC
Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.
    
 0.958
G3NPU8_GASAC
Uncharacterized protein.
    
 0.854
G3NPV2_GASAC
Uncharacterized protein.
    
 0.854
G3NWN2_GASAC
Mitochondrial fission factor.
   
 0.847
G3NWQ1_GASAC
Mitochondrial ribosomal protein L44.
    
 0.847
G3PT28_GASAC
Miff domain-containing protein.
    
 0.847
AGO3
Argonaute RISC catalytic component 3; Belongs to the argonaute family.
    
 0.831
EIF2C4
Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.
    
 0.831
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 0.831
G3PFT0_GASAC
Argonaute RISC component 1; Belongs to the argonaute family.
    
 0.831
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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