Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3N8Y3_GASACZinc finger, MYM-type 2. (1193 aa)    
Predicted Functional Partners:
G3P5C3_GASAC
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
   
 0.997
G3PMN0_GASAC
DDE Tnp4 domain-containing protein.
      
 0.878
G3NBE0_GASAC
Si:ch211-173p18.3.
   
   0.833
UBQLN4
Ubiquilin 4.
    
 0.833
G3PGR1_GASAC
Uncharacterized protein.
   
   0.833
G3NJU0_GASAC
Activity-dependent neuroprotector homeobox b.
   
 
 0.829
G3N5V1_GASAC
Ras responsive element binding protein 1a.
   
 0.814
G3NG90_GASAC
Ubiquitin-conjugating enzyme E2C.
     
 0.814
G3P6C2_GASAC
BUD23 rRNA methyltransferase and ribosome maturation factor.
    
   0.800
G3Q7M0_GASAC
REST corepressor 3.
   
 
 0.797
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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