STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3N907_GASACSerine peptidase inhibitor, Kunitz type, 2. (369 aa)    
Predicted Functional Partners:
G3P432_GASAC
Transmembrane serine protease 13b; Belongs to the peptidase S1 family.
   
 0.818
G3PIA1_GASAC
Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix.
   
 0.809
HGFAC
HGF activator.
    
 0.797
G3N8R7_GASAC
Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.788
G3PGI4_GASAC
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.788
G3Q8D9_GASAC
Hepatocyte growth factor a; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.788
G3NG49_GASAC
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.787
G3NGC8_GASAC
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.787
G3NGH9_GASAC
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.787
G3NWZ0_GASAC
Serine protease 1; Belongs to the peptidase S1 family.
   
 0.787
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.