STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3N9C4_GASACGeneral transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (459 aa)    
Predicted Functional Partners:
G3NHZ7_GASAC
General transcription factor IIH subunit.
   
 0.999
G3NQB0_GASAC
General transcription factor IIH, polypeptide 1.
    
 0.999
G3NZD7_GASAC
General transcription factor IIH, polypeptide 3.
   
 0.999
G3P229_GASAC
General transcription factor IIH, polypeptide 5.
    
 0.999
G3PFN5_GASAC
Excision repair cross-complementation group 2.
   
 0.999
G3PR46_GASAC
Excision repair cross-complementation group 3.
  
 0.999
G3NWX0_GASAC
General transcription factor IIE, polypeptide 1, alpha.
   
 0.998
G3P0R7_GASAC
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
   
 0.998
G3PTP8_GASAC
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 0.997
G3P7H1_GASAC
Cyclin H; Belongs to the cyclin family.
    
 0.992
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.