Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RRM2Ribonucleotide reductase regulatory subunit M2. (389 aa)    
Predicted Functional Partners:
G3QAM4_GASAC
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.991
G3P5J9_GASAC
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.989
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.907
G3PBE5_GASAC
Cyclin F; Belongs to the cyclin family.
   
 
 0.865
G3PC67_GASAC
Uncharacterized protein.
    
 0.861
G3PC70_GASAC
Uncharacterized protein.
    
 0.861
G3PC74_GASAC
Uncharacterized protein.
    
 0.861
G3PK90_GASAC
Cell division cycle 20 homolog.
   
 
 0.860
G3PC58_GASAC
Uncharacterized protein; Belongs to the adenylate kinase family.
    
 0.858
G3NJA3_GASAC
Thymidylate synthetase.
   
  
 0.847
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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