Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3N9G6_GASACInsulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (239 aa)    
Predicted Functional Partners:
G3PGG5_GASAC
SREBF chaperone.
    
 0.947
G3N8K5_GASAC
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
 
 0.939
G3NHN3_GASAC
Chromatin assembly factor 1, subunit B.
   
 
 0.882
G3PT43_GASAC
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
 
 0.875
G3NQJ7_GASAC
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 
 0.842
G3P4T2_GASAC
Ring finger protein 139.
    
 
 0.809
G3PVF0_GASAC
Autocrine motility factor receptor b.
    
 
 0.802
G3Q4E9_GASAC
Synovial apoptosis inhibitor 1, synoviolin.
    
 
 0.802
G3Q390_GASAC
Fas associated factor family member 2.
    
 
 0.794
G3P597_GASAC
Valosin containing protein; Belongs to the AAA ATPase family.
   
 
 0.752
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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