STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3N9G6_GASACInsulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (239 aa)    
Predicted Functional Partners:
G3PGG5_GASAC
SREBF chaperone.
    
 0.928
G3NHN3_GASAC
Chromatin assembly factor 1, subunit B.
    
 
 0.890
G3N8K5_GASAC
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
 
 0.825
G3Q939_GASAC
Origin recognition complex, subunit 5.
    
   0.810
G3PT43_GASAC
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
 
 0.809
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
    
 0.792
G3PZ00_GASAC
Niemann-Pick disease, type C1.
    
 0.792
G3P8A4_GASAC
Anti-silencing function 1Ba histone chaperone.
   
 
 0.714
G3Q4V8_GASAC
Anti-silencing function 1Ba histone chaperone.
   
 
 0.714
G3NQJ7_GASAC
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.701
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.