Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3N9X2_GASACCytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (420 aa)    
Predicted Functional Partners:
G3N956_GASAC
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.
  
 0.987
G3PKF1_GASAC
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family.
  
 0.987
G3P7W5_GASAC
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
  
 0.986
G3P886_GASAC
Cholesterol 25-hydroxylase like 1, tandem duplicate 1; Belongs to the sterol desaturase family.
  
 0.986
G3PT58_GASAC
Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family.
  
 0.986
G3PIW8_GASAC
Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family.
  
 0.981
G3ND98_GASAC
Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family.
  
 
 0.966
G3NLK7_GASAC
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
 
0.963
G3NDL3_GASAC
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 0.953
G3PNM9_GASAC
Si:dkey-91i10.3; Belongs to the cytochrome P450 family.
  
 
0.950
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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