Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
G3NAB1_GASACAutophagy protein 5; Involved in autophagic vesicle formation. (275 aa)    
Predicted Functional Partners:
G3P8T6_GASAC
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
   
 0.999
G3PRD2_GASAC
Autophagy-related protein 3.
   
 0.999
G3N943_GASAC
ATG16 autophagy related 16-like 1 (S. cerevisiae).
   
 0.998
G3N3Z7_GASAC
Microtubule-associated protein 1 light chain 3 alpha.
    
 0.995
G3NFR5_GASAC
Microtubule-associated protein 1 light chain 3 beta.
    
 0.995
G3NWL2_GASAC
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
    
 0.995
G3PPE9_GASAC
Autophagy_act_C domain-containing protein.
    
 0.995
G3Q6X5_GASAC
GABA(A) receptor-associated protein b.
    
 0.992
G3NBV8_GASAC
GABA(A) receptor-associated protein like 2.
    
 0.991
G3PZT6_GASAC
Uncharacterized protein.
    
 0.991
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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