STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NAB1_GASACAutophagy protein 5; Involved in autophagic vesicle formation. (275 aa)    
Predicted Functional Partners:
G3P8T6_GASAC
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
   
 0.999
G3PRD2_GASAC
Autophagy-related protein 3.
   
 0.996
G3PEL2_GASAC
Tectonin beta-propeller repeat containing 1b.
    
 0.994
G3N943_GASAC
ATG16 autophagy related 16-like 1 (S. cerevisiae).
   
 0.992
G3NL10_GASAC
WD_REPEATS_REGION domain-containing protein.
   
 0.992
G3NWL2_GASAC
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
    
 0.963
G3Q6X5_GASAC
GABA(A) receptor-associated protein b.
   
 0.947
G3NBV8_GASAC
GABA(A) receptor-associated protein like 2.
   
 0.946
G3PZT6_GASAC
Uncharacterized protein.
   
 0.946
G3NYU7_GASAC
WD repeat domain, phosphoinositide interacting 2.
    
 0.945
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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