Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NAB8_GASACPR domain containing 1a, with ZNF domain. (694 aa)    
Predicted Functional Partners:
G3P2W1_GASAC
DNA-binding protein SATB.
      
 0.788
G3P4E5_GASAC
Uncharacterized protein.
    
   0.761
G3NK71_GASAC
SRY-box transcription factor 17.
    
 0.753
G3PMA4_GASAC
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.753
G3NMP9_GASAC
Forkhead box Q1b.
    
 
 0.733
G3Q5G3_GASAC
Nanos homolog 3; Belongs to the nanos family.
     
 0.725
G3PMH0_GASAC
Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.
    
 
 0.701
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.696
SOX18
SRY-box transcription factor 18.
    
 0.695
G3NE50_GASAC
Exostoses (multiple) 1c; Belongs to the glycosyltransferase 47 family.
      
 0.690
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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