STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NAR4_GASACE3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)    
Predicted Functional Partners:
G3PKR3_GASAC
Calcyclin binding protein.
    
 0.981
G3NRM5_GASAC
Catenin (cadherin-associated protein), beta 1.
    
 0.939
G3NRF1_GASAC
Uncharacterized protein.
    
 0.911
UBE2N
Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.856
G3Q4R3_GASAC
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.854
G3Q1E3_GASAC
Ubiquitin-conjugating enzyme E2 variant 2.
   
   0.838
G3PW48_GASAC
Uncharacterized protein; Belongs to the synuclein family.
   
 0.819
G3PBS8_GASAC
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
   0.799
G3N550_GASAC
Uncharacterized protein.
    
 0.786
G3Q2Y3_GASAC
Junction plakoglobin a.
    
 0.786
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: medium (56%) [HD]