Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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G3NAR4_GASACE3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)    
Predicted Functional Partners:
G3PW48_GASAC
Uncharacterized protein; Belongs to the synuclein family.
    
 0.934
G3PKR3_GASAC
Calcyclin binding protein.
    
 
 0.926
G3NRM5_GASAC
Catenin (cadherin-associated protein), beta 1.
    
 
 0.876
G3Q1E3_GASAC
Ubiquitin-conjugating enzyme E2 variant 2.
    
   0.834
G3P046_GASAC
Dihydrolipoyl dehydrogenase.
    
   0.821
G3NEI4_GASAC
Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.
    
 0.773
UBE2N
Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.770
G3Q4R3_GASAC
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.770
G3NRA1_GASAC
Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
 
 0.754
G3P6K9_GASAC
Ubiquitinyl hydrolase 1.
    
 0.754
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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