Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NAX5_GASACSERPIN domain-containing protein; Belongs to the serpin family. (412 aa)    
Predicted Functional Partners:
G3N651_GASAC
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.922
G3NGY3_GASAC
Interferon induced transmembrane protein 5.
    
 0.786
G3PRZ3_GASAC
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
 0.769
G3PT67_GASAC
Uncharacterized protein.
  
 0.754
G3NLV8_GASAC
Cartilage associated protein.
     
 0.748
G3NSP8_GASAC
Peptidylprolyl isomerase.
   
 
 0.747
G3PAJ6_GASAC
Prolyl 3-hydroxylase 1.
     
 0.726
G3PK17_GASAC
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
  
0.698
G3Q7G4_GASAC
SEC24 homolog D, COPII coat complex component.
     
 0.696
TMEM38B
Transmembrane protein 38B.
      
 0.673
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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