STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NAX5_GASACSERPIN domain-containing protein; Belongs to the serpin family. (412 aa)    
Predicted Functional Partners:
G3N651_GASAC
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.866
G3PRZ3_GASAC
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.843
G3PT67_GASAC
Uncharacterized protein.
  
  0.741
G3NGY3_GASAC
Interferon induced transmembrane protein 5.
    
 0.713
G3P167_GASAC
Vitronectin a.
   
 0.683
G3QB08_GASAC
Vitronectin b.
   
 0.683
G3PK17_GASAC
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
  
 
0.665
HGFAC
HGF activator.
  
 0.662
G3NHR1_GASAC
Uncharacterized protein.
  
 0.625
G3NTF8_GASAC
Hyaluronan binding protein 2.
  
 0.625
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.