| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COQ3 | COQ6 | ENSGACP00000006584 | ENSGACP00000010367 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.984 |
| COQ3 | G3NB00_GASAC | ENSGACP00000006584 | ENSGACP00000002496 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Flavin-containing monooxygenase. | 0.710 |
| COQ3 | G3P697_GASAC | ENSGACP00000006584 | ENSGACP00000013120 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family. | 0.576 |
| COQ3 | G3PS84_GASAC | ENSGACP00000006584 | ENSGACP00000020470 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Epoxide hydrolase 2, cytoplasmic. | 0.860 |
| COQ3 | KMO | ENSGACP00000006584 | ENSGACP00000003896 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.935 |
| COQ6 | COQ3 | ENSGACP00000010367 | ENSGACP00000006584 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.984 |
| COQ6 | G3NB00_GASAC | ENSGACP00000010367 | ENSGACP00000002496 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Flavin-containing monooxygenase. | 0.740 |
| COQ6 | G3P697_GASAC | ENSGACP00000010367 | ENSGACP00000013120 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family. | 0.616 |
| COQ6 | G3PRV3_GASAC | ENSGACP00000010367 | ENSGACP00000020339 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). | 0.853 |
| COQ6 | G3PS84_GASAC | ENSGACP00000010367 | ENSGACP00000020470 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Epoxide hydrolase 2, cytoplasmic. | 0.698 |
| COQ6 | KMO | ENSGACP00000010367 | ENSGACP00000003896 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.534 |
| G3NB00_GASAC | COQ3 | ENSGACP00000002496 | ENSGACP00000006584 | Flavin-containing monooxygenase. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.710 |
| G3NB00_GASAC | COQ6 | ENSGACP00000002496 | ENSGACP00000010367 | Flavin-containing monooxygenase. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.740 |
| G3NB00_GASAC | G3NMJ1_GASAC | ENSGACP00000002496 | ENSGACP00000006554 | Flavin-containing monooxygenase. | Hydroxyacid oxidase (glycolate oxidase) 1. | 0.740 |
| G3NB00_GASAC | G3P697_GASAC | ENSGACP00000002496 | ENSGACP00000013120 | Flavin-containing monooxygenase. | Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family. | 0.722 |
| G3NB00_GASAC | G3PHA5_GASAC | ENSGACP00000002496 | ENSGACP00000016980 | Flavin-containing monooxygenase. | Tr-type G domain-containing protein. | 0.702 |
| G3NB00_GASAC | G3PRF7_GASAC | ENSGACP00000002496 | ENSGACP00000020192 | Flavin-containing monooxygenase. | Eukaryotic translation elongation factor 2b. | 0.701 |
| G3NB00_GASAC | G3PRP5_GASAC | ENSGACP00000002496 | ENSGACP00000020281 | Flavin-containing monooxygenase. | Regucalcin. | 0.702 |
| G3NB00_GASAC | G3PRV3_GASAC | ENSGACP00000002496 | ENSGACP00000020339 | Flavin-containing monooxygenase. | Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). | 0.749 |
| G3NB00_GASAC | G3PS84_GASAC | ENSGACP00000002496 | ENSGACP00000020470 | Flavin-containing monooxygenase. | Epoxide hydrolase 2, cytoplasmic. | 0.693 |