STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-. (903 aa)    
Predicted Functional Partners:
G3N7F9_GASAC
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.903
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.903
G3NPM9_GASAC
ATP-dependent Clp protease proteolytic subunit.
  
 
 0.858
G3NDU0_GASAC
Neurochondrin.
     
 0.851
G3NRD5_GASAC
Caseinolytic mitochondrial matrix peptidase chaperone subunit b.
 
 
 0.841
G3P196_GASAC
Trypsin domain containing 1.
  
 0.828
G3P2P7_GASAC
Heat shock 60 protein 1; Belongs to the chaperonin (HSP60) family.
  
 0.779
G3PVL4_GASAC
YME1-like 1b.
  
 
 0.769
G3PUT5_GASAC
Sterol carrier protein 2a; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.754
G3Q8L9_GASAC
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
  
 0.734
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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