| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FEN1 | G3NDJ8_GASAC | ENSGACP00000002941 | ENSGACP00000003398 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.944 |
| FEN1 | G3NE68_GASAC | ENSGACP00000002941 | ENSGACP00000003619 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.946 |
| FEN1 | G3NQJ7_GASAC | ENSGACP00000002941 | ENSGACP00000007613 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.995 |
| FEN1 | G3P3Z7_GASAC | ENSGACP00000002941 | ENSGACP00000012320 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.970 |
| FEN1 | G3PDF4_GASAC | ENSGACP00000002941 | ENSGACP00000015628 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Polymerase (DNA directed), delta 2, regulatory subunit. | 0.960 |
| FEN1 | G3PHK7_GASAC | ENSGACP00000002941 | ENSGACP00000017083 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.989 |
| FEN1 | G3PQC5_GASAC | ENSGACP00000002941 | ENSGACP00000019810 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | RecQ helicase-like 4. | 0.951 |
| FEN1 | G3PUG9_GASAC | ENSGACP00000002941 | ENSGACP00000021256 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA replication helicase/nuclease 2. | 0.963 |
| FEN1 | G3Q0G8_GASAC | ENSGACP00000002941 | ENSGACP00000023360 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.986 |
| FEN1 | G3QBA9_GASAC | ENSGACP00000002941 | ENSGACP00000027175 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Replication factor C (activator 1) 3. | 0.952 |
| G3NDJ8_GASAC | FEN1 | ENSGACP00000003398 | ENSGACP00000002941 | DNA polymerase. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.944 |
| G3NDJ8_GASAC | G3NE68_GASAC | ENSGACP00000003398 | ENSGACP00000003619 | DNA polymerase. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.740 |
| G3NDJ8_GASAC | G3NQJ7_GASAC | ENSGACP00000003398 | ENSGACP00000007613 | DNA polymerase. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.994 |
| G3NDJ8_GASAC | G3P3Z7_GASAC | ENSGACP00000003398 | ENSGACP00000012320 | DNA polymerase. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.779 |
| G3NDJ8_GASAC | G3PDF4_GASAC | ENSGACP00000003398 | ENSGACP00000015628 | DNA polymerase. | Polymerase (DNA directed), delta 2, regulatory subunit. | 0.982 |
| G3NDJ8_GASAC | G3PHK7_GASAC | ENSGACP00000003398 | ENSGACP00000017083 | DNA polymerase. | DNA polymerase. | 0.977 |
| G3NDJ8_GASAC | G3PQC5_GASAC | ENSGACP00000003398 | ENSGACP00000019810 | DNA polymerase. | RecQ helicase-like 4. | 0.918 |
| G3NDJ8_GASAC | G3PUG9_GASAC | ENSGACP00000003398 | ENSGACP00000021256 | DNA polymerase. | DNA replication helicase/nuclease 2. | 0.918 |
| G3NDJ8_GASAC | G3Q0G8_GASAC | ENSGACP00000003398 | ENSGACP00000023360 | DNA polymerase. | DNA ligase. | 0.924 |
| G3NDJ8_GASAC | G3QBA9_GASAC | ENSGACP00000003398 | ENSGACP00000027175 | DNA polymerase. | Replication factor C (activator 1) 3. | 0.946 |