Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NCQ5_GASACDNA-damage-inducible transcript 4. (229 aa)    
Predicted Functional Partners:
G3Q5B2_GASAC
TSC complex subunit 2.
    
 0.997
G3NA02_GASAC
Uncharacterized protein.
   
 
 0.922
G3Q268_GASAC
TSC complex subunit 1b.
   
 
 0.922
G3NMC3_GASAC
TBC1 domain family, member 7.
     
 0.908
G3P177_GASAC
Uncharacterized protein.
  
  
 
0.904
G3P206_GASAC
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
 
 0.887
G3NPB4_GASAC
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1; Belongs to the 14-3-3 family.
   
 0.810
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.790
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family.
   
 0.787
G3NH36_GASAC
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
   
 0.787
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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